eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2024-09-30 17 3 1461 1469 10.13005/bpj/2956 60689 article Mariia Shanaida 1 Olha Korablova 2 Dzhamal Rakhmetov 2 Bohdanna Sydor 1 Volodymyr Shanaida 3 Nataliia Hudz 4 Department of Pharmacognosy and Medical Botany, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine M.M. Gryshko National Botanical Garden, National Academy of Sciences of Ukraine, Kyiv, Ukraine Design of Machine Tools, Instruments and Machines Department, Ternopil Ivan Puluj National Technical University, Ternopil, Ukraine; Department of Pharmacy and Ecological Chemistry, University of Opole, Opole, Poland Department of Drug Technology and Biopharmacy, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Nitra, Slovakia This study aimed to analyze the compositions of flavonoids and phenolic acids in the aerial parts of two Artemisia L. species (Artemisia ludoviciana Nutt. and Artemisia campestris L.) when grown in Ukraine. High-performance liquid chromatography analysis (HPLC) detected the presence of 11 flavonoids and 10 phenolic acids in the plant materials under study. Among the phenolic acids, chlorogenic acid was the most abundant in the raw material of both species (14.503 mg/g in Artemisia ludoviciana and 4.504 mg/g in Artemisia campestris). The main flavonoids in the Artemisia ludoviciana herb decreased in the following order: flavanone-7-O-glycoside (naringin) (21.924 mg/g) > fisetin (13.068 mg/g) > kaempferol-3-b-glucoside (5.119 mg/g) > rutin (1.295 mg/g). In comparison, in Artemisia campestris raw material the order was: flavanone-7-O-glycoside (7.525 mg/g) > fisetin (2.933 mg/g) > rutin (1.355 mg/g). Since the predominant polyphenols have demonstrated valuable therapeutic potential, the data obtained could be considered for further exploration of their biological activities. https://biomedpharmajournal.org/vol17no3/chromatographic-profiles-of-polyphenols-in-the-herbs-of-artemisia-campestris-l-and-artemisia-ludoviciana-nutt/ Aerial part Artemisia species Flavonoids High-performance Liquid Chromatography Phenolic acids