eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2023-09-30 16 3 1441 1450 10.13005/bpj/2722 51249 article D.Manoharan 1 Shreya Srinivasan 1 Vignesh N R 1 Aswin Senthilvel 1 Department of Dermatology, Venereology & Leprosy, Sree Balaji Medical College & Hospital, Chennai, India The most frequently prescribed antibiotic class in dermatology is the tetracycline family, which has both antibacterial and anti-inflammatory characteristics. Tetracycline is a broad-spectrum polyketide antibiotic effective against gram-positive and gram-negative organisms. It has been accepted for the therapeutic use of various conditions in dermatology like Acne, Rosacea, Syphilis, Immuno-bullous dermatoses, Pyoderma gangrenosum and Hidradenitis Suppurativa to name a few. However, the use and efficacy of newly discovered tetracyclines like Sarecycline, Omadacycline and Tigecycline are still yet to be documented and researched. In this study, a short summary of the utilization of various tetracycline are being documented for their use in dermatology. https://biomedpharmajournal.org/vol16no3/tetracyclines-the-old-the-new-and-the-improved-a-short-review/ Anti-Inflammatory Doxycycline Minocycline Tetracycline