eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2022-12-20 15 4 2115 2123 10.13005/bpj/2548 46589 article Fayez K. Fouda 1 Ahmed Saad Montaser 2 Gehan T. El-Bassyouni 3 Esmat M.A. Hamzawy 4 Eman RefaatYouness 5 Mohamed S. Abd El-Aziz 6 Medical Biochemistry Department, Medical Research and clinical studies Institute,National Research Centre, Doki, Giza, Egypt Textile Research Institute, National Research Centre, Cairo, Giza, Egypt. Refractories, Ceramics and Building Materials Dept., National Research Centre, Dokki, Cairo, Egypt. Glass Research Dept., National Research Centre, Dokki, Cairo, Egypt. Medical Biochemistry Department,Medical Research and clinical studies Institute, National Research Centre, Doki, Giza, Egypt Genetic Engineering and Biotechnology Institute, Microbial Chemistry Department, National Research Centre (NRC), Dokki, Egypt Aspergillosis is a fungal infection cause reduction or suppression of innate immune system. Occasionally silver nanoparticles showed antibacterial activity rather than anti-fungal activity. In the current paper three different shapes and concentrations of silver nanoparticles (AgNPs) were synthesized using dextrin and starch, then applied to cotton for acquiring antifungal properties.   TEM illustrates the size, shape and homogeneity of the AgNPs. Atomic absorption spectroscopy (AAS) quantified the AgNPs in the colloidal solution. Attenuated total reflection ATR/FT-IR spectroscopy and scanning electron microscope (SEM) coupled with Energy Dispersive X-Ray Analysis (EDX) to screen the homogeneity and dispersion of the AgNPs. Different shapes (rode and triangular) of AgNPs (10-17nm) were produced using 10~5 ppm of the AgNPs. Antifungal activity towards Aspergillus Niger fungus was documented using the disc diffusion method. Cotton treated with AgNPs showed significant effective antifungal properties at lower concentrations (~10 ppm) preserving its white color compared to the higher concentrations (>100 ppm)of the AgNPs. Manufactured cotton fabrics treated with low concentrations of AgNPs were examined towards the recognition of the antifungal properties with minimal industrial footprint which may expose a novelpossibility for antifungal applications. https://biomedpharmajournal.org/vol15no4/eco-friendly-low-concentration-silver-nanoparticles-acquiring-cotton-textile-antifungal-activities-for-pulmonary-aspergillosis-protection/ Anti-Fungal  Aspergillosis  Cotton Textile  Silver Nanoparticles  Tissue Resist Fungus