eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2021-12-30 14 4 1799 1813 10.13005/bpj/2279 41886 article Vanshika Shrivastava 1 Naveen Sharma 2 Vikas Shrivastava 1 Ajay Sharma 3 Amity Institute of Biotechnology, Amity University Madhya Pradesh Gwalior, India-474005 Amity Institute of Pharmacy, Amity University Madhya Pradesh Gwalior, India-474005 Department. of Pharmacognocy, Delhi Pharmaceutical sciences and Research University, New Delhi-110017 Nothapodytes nimmoniana is an endangered medicinal plant widely distributed throughout the Western Ghats of India. The plant contains camptothecin (CPT) which is renowned anticancer drugs. Though, CPT found in many plant species but maximum amount of CPT has been reported from N. nimmoniana. Due to very good source of CPT, this plant has been explored for its Phytochemical, Biotechnological and Pharmacological aspects. Looking to the huge global demand for CPT, overexploitation of N. nimmoniana, unplanned deforestation, and lowest production of CPT from intact plant, reduction of seed germination, high market cost and not have economically feasible process of production has optimistic us to investigate this plant in a systematic manner. The proposed article can be utilized for the establishment of extraction methods and analytical protocol for CPT. Also, Bioreactors production of CPT using high yielding cell line of N. nimmoniana. The pharmacological data will be applicable for discovery of new Drug and development lead to novel compounds which are safe and effective. https://biomedpharmajournal.org/vol14no4/review-on-camptothecin-producing-medicinal-plant-nothapodytes-nimmoniana/ Anticancer  Camptothecin  Biotechnological  Nothapodytes Nimmoniana  Medicinal plant  Pharmacological