eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2021-12-30 14 4 1983 1991 10.13005/bpj/2296 41892 article Nagham Mahmood Aljamali 1 Sabrean Farhan Jawad 2 Department of Chemistry ,Synthetic Organic Chemistry ,Iraq. Department of Pharmacy, Al-Mustaqbal University College, Babylon, Iraq The importance of research lies in the treatment of cancerous tumors due to the spread of cancerous tumors in recent decades, so researchers have to insist on finding alternative and more treatments safe from chemotherapy and radiation, which are derivatives of some amino acids, which we attended in our current research. Also, some research showed that taking tryptophan for 3 days before exercise can improve energy and efficiency during exercise, but other preliminary research shows that taking tryptophan during exercise does not improve endurance during cycling exercises. For a few days before exercise to notice any benefit. In this research, we prepared derivatives of cyclic tryptophan and studied their efficacy as anti-tumors, and they gave good results in reducing the size of cancerous tumors and reducing their spread in the body., then sympathy all synthesized  new cyclic-tryptophan compounds  by numerous techniques (FT.IR ,H.NMR)–spectrophotometric, other  physical and chemical properties ,with studying for one of  new prepared  derivatives as anti breast cancer. https://biomedpharmajournal.org/vol14no4/preparation-diagnosis-and-evaluation-of-cyclic-tryptophan-derivatives-as-anti-breast-cancer-agents/ Anti Breast Anticancer Heterocyclic Tryptophan  Triazole