eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2021-12-30 14 4 1791 1797 10.13005/bpj/2278 41817 article Efficacy and Mechanism of Action of Aloe Vera, Cinnamomum Zeylanicum, Curcuma Longa, Garcinia Cambogia, and Garcinia Mangostana Extracts in Lowering Body Weight in Obesity: A Literature Review Eko Fuji Ariyanto 1 Nurul Ovifa Multom 2 Afiat Berbudi 3 Enny Rohmawaty 4 Budi Sujatmiko 5 Division of Biochemistry and Molecular Biology, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jl. Raya Bandung Sumedang, KM. 21, Sumedang, Indonesia, 45363. Medical Program, Faculty of Medicine, Universitas Padjadjaran, Jl. Raya Bandung Sumedang, KM. 21, Sumedang, Indonesia, 45363. Division of Parasitology, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jl. Raya Bandung Sumedang, KM. 21, Sumedang, Indonesia, 45363. Division of Pharmacology and Therapy, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jl. Raya Bandung Sumedang, KM. 21, Sumedang, Indonesia, 45363. 5Division of Epidemiology, Department of Public Health, Faculty of Medicine, Universitas Padjadjaran, Jl. Raya Bandung Sumedang, KM. 21, Sumedang, Indonesia, 45363. The habits of today's society, which are influenced by economic growth and globalization have brought new lifestyles, especially those related to diet, resulting in minimal physical activity accompanied by a high calorie intake. This energy imbalance can lead to the metabolic syndrome, including obesity, which is still a burden on the world today. Some plants in Indonesia are believed to help lose weight, such as Aloe vera, Cinnamomum zeylanicum, Curcuma longa, Garcinia cambogia, and Garcinia mangostana. This literature review was conducted to determine the effects of Aloe vera, Cinnamomum zeylanicum, Curcuma longa, Garcinia cambogia, and Garcinia mangostana on weight loss and preventing obesity. The review of twelve relevant articles concluded that Aloe vera, Cinnamomum zeylanicum, Curcuma longa, Garcinia cambogia, and Garcinia mangostana have the potential to prevent and treat obesity but further research is required. https://biomedpharmajournal.org/vol14no4/efficacy-and-mechanism-of-action-of-aloe-vera-cinnamomum-zeylanicum-curcuma-longa-garcinia-cambogia-and-garcinia-mangostana-extracts-in-lowering-body-weight-in-obesity-a-literature-review/ Aloe Vera Cinnamomum Zeylanicum Curcuma Longa Garcinia Cambogia Garcinia Mangostana Obesity Weight Loss