eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2021-09-30 14 3 1519 1523 10.13005/bpj/2253 40007 article Amandeep Singh Bakshi 1 Neetu Sharma 2 Jasbir Singh 2 Sandeep Batish 3 Vijay Sehgal 1 Department of Orthopedics, Govt. Medical College , Patiala. India Department of Pharmacology, Govt. Medical College , Patiala. India Deputy Civil Surgeon , Kaithal , Haryana. India Objectives : Novel coronavirus disease COVID-19  has emerged as a pandemic, claiming over 1,431,513  lives ( till Nov. 27,2020 ) worldwide involving 191 countries . The objective of the study is to evaluate age and gender as a risk factor for COVID -19 related mortality . Material and Methods : It is a retrospective cohort study , where the database of indoor COVID-19 positive patients was assessed for the study. Evaluation of the role of age and gender in mortality of COVID infection by comparing dataset of 2,142 indoor COVID positive patients with two outcome groups namely ,death and discharged groups was done. Results: The  age comparison between two groups namely, death and discharged groups  showed a median age of 60 years (IQR 50-70) for patients who died and 52 years (IQR 36–62) for the patients who recovered from COVID (p value-<0.001). There were 9 (0.65%) pediatric patients (<12 yrs) in the group of patients who recovered .For gender analysis (n=2129), COVID patients who died were 32.5%( n=692) ,out of which 63.6%(n=440) were males and 36.4%(n=252) were females. COVID positive patients in discharged group were 67.5%(n=1437),out of which 61.2%(n=880) were males and 38.8%(n=557) were females. There was no statistical difference between the two groups for mortality risk based on gender for COVID -19 infection (chi square value of 1.09, p value=.296) and the relative risk of death in males and females who died of COVID was 1.052 (95% CI=0.92-1.204). Conclusion: COVID-19 infection is showing predilection for male gender in both death and discharged group but the males and females are equally susceptible to the risk of death . https://biomedpharmajournal.org/vol14no3/to-study-demographics-as-risk-factor-for-mortality-associated-with-covid-19-a-retrospective-cohort-study/ COVID-19  Demographics  Mortality risk  risk factors