eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2021-09-30 14 3 1109 1124 10.13005/bpj/2214 40778 article Sachin Chaudhary 1 Abdel-Nasser El-Shorbagi1 1 Ramesh Kumar Gupta2 2 Amit Kumar 3 Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates, 27272 Department of Pharmacology,Hygia Institute of Pharmaceutical Education and Research Lucknow, Uttar Pradesh, India, 226020 School of Pharmaceutical Sciences, IIMT University, Meerut, Uttar Pradesh, India, 250001, The Covid-19 pandemic since 2019 has imparted a massive influence on the human life around the world, irrespective of all the precautionary measures followed worldwide it is strongly suggested that only the effective and safer vaccine can control this vicious pandemic. Nevertheless, the vaccine development strategies for Covid-19 was initiated firstly in china after the outbreak of Covid-19 and then globally after it was declared as pandemic by World Health Organization. Currently, numerous platforms have been designed for developing the most efficacious and safe vaccines designed by different technologies including protein subunit, viral vector, RNA, DNA, inactivated, and live attenuated approach. Here, this review will illustrates the detailed information on above mentioned Covid-19 vaccines development technologies, protocols and their clinical trial phase status. Additionally, this review also includes the details of vaccines failed to progress further. https://biomedpharmajournal.org/vol14no3/the-recent-updates-on-approaches-and-clinical-trials-status-of-covid-19-vaccines-developed-globally-s/ Clinical trial Covid-19  Inactivated Live attenuated  SARS-CoV-2  Vaccine