eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2020-12-30 13 4 1871 1878 10.13005/bpj/2062 36082 article Rike Syahniar 1 Rayhana 1 Dayu Swasti Kharisma 1 Muhammad Khatam 2 Dimas Bagus Bramasta Duarsa 2 Department of Microbiology and Parasitology, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta, Indonesia Undergraduate Student, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta, Indonesia. BACKGROUND: The high infection of methicillin-resistant Staphylococcus aureus (MRSA) accompanied by increased resistance to many groups of antibiotics is a major concern in the field of infection. This study aims to evaluate the prevalence of MRSA isolates and antimicrobial susceptibility to MRSA isolates in Indonesia. METHODS: We did searches in Pubmed, Proquest, DOAJ, GARUDA, and google scholar for studies published in 2006-2020. Study in Indonesian (Bahasa) and English with the keywords "methicillin-resistant Staphylococcus aureus", "MRSA" and "Indonesia". More than 30 S.aureus isolates derived from human samples were included. RESULTS: A total of 738 articles based on the search results, 13 studies were included in this systematic review. The prevalence of MRSA reported from all studies is 0.3%-52%. The study with the largest prevalence of MRSA was found in Jakarta. The susceptibility of vancomycin antibiotics to MRSA isolates is known to range from 87%-100%. Based on all studies, Linezolid, Tigecycline, Nitrofurantoin, and quinupristin/dalfopristin were reported to have 100% susceptibility. CONCLUSIONS: The prevalence of MRSA is still found high in one of the cities in Indonesia. Surveillance of antibiotic use, monitoring of antimicrobial susceptibility patterns, and antibiotic resistance control programs need to be optimized. MRSA screening is based on a rapid diagnosis when an inpatient admission is also necessary. https://biomedpharmajournal.org/vol13no4/methicillin-resistant-staphylococcus-aureus-among-clinical-isolates-in-indonesia-a-systematic-review/ Indonesia  Methicillin-Resistant Staphylococcus Aureus  Systematic Review