eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2020-12-30 13 4 1899 1902 10.13005/bpj/2066 35508 article Renuka P 1 Somnath Bag 1 Vinodhini V. M 1 Department of Biochemistry, SRM Medical College Hospital and Research Centre, Kattankulathur, Kancheepuram District- 603203, Tamil Nadu, India. The use of HbA1c in diagnosis of diabetes mellitus by WHO and ADA has come under scrutiny. Aim: To study the erythrocyte index alterations and their relationship with HbA1c for proper interpretation of HbA1c values in diabetic subjects. Materials and methods: Data from 301 diabetic patients was collected. The parameters included were fasting plasma glucose, red blood cell count, hemoglobin level, hematocrit, glycated Hemoglobin (HbA1c), MCV, MCH, MCHC and RDW. Results: A negative correlation was found between HbA1c and MCV, MCH and MCHC and positive correlation with RDW. Conclusion: Hematological parameters like MCH, MCV and MCHC should be taken into account in interpreting HbA1c levels in diagnosis and management of pre diabetes and diabetes. https://biomedpharmajournal.org/vol13no4/hemorheological-indices-and-glycated-hemoglobin-in-type-2-diabetes-mellitus/ Diabetes Mellitus  Glycated Hemoglobin  MCH  MCHC  MCV  RDW