eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2020-12-30 13 4 1921 1926 10.13005/bpj/2069 35694 article Swapna R Nayaka 1 Sabari Anand J V 2 Shaik Mabu Shareef 3 Usha N S 1 Department of Pharmacology, MVJ Medical College and Research Hospital, Hoskote - 562114, India. Department of Pharmacology, MGMC, and RI, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India. Department of Pharmacology, Kurnool Medical College, Kurnool - 518002, Andhra Pradesh, India. Seaweeds (Marine macroalgae) area large group of marine organisms containing important phytochemical constituents with various biologicalactivities .They are potentially prolific sources of highly bioactivese condary metabolites, which manifest many of the rapeutic effects  like anti-cancer, anti-oxidant, anti-inflammatory and anti-diabetic activities. Seaweeds are used  by many Asian cultures fortraditional medicine preparations. The Caulerpapeltata was collected from Rameshwaram coastal area it was shadedried, madein to powder using standardized procedure to get Caulerpapeltata Methanolic Extract (CPME). The phytochemicals and Gas Chromatography-Mass Spectrometry (GC-MS) analysis was done on prepared CPME for identifying the bioactive compounds Phytochemical in vestigation suggests that the Caulerpapeltata exhibited the presence of phytochemicals like Alkaloids, Carbohydrates, Phytosterols, Saponins and Diterpenes,which may contribute to its biological activities. GC-MS analysis showed 28 variety  of compounds,among which Dibutylphthalate, n-hexadecanoic acid, and1,2–Benzenedic arboxylic acid was found in high percentage. The phytochemical studies and the compounds available in GC–MS showed that the Caulerpapeltata contain important bio active compounds,which may have anti-microbial,anti-fungal and anti-canceractivity. Further research is needed for finding its use in development of new pharmaceutical agent and its safe consumption by human for various health benefits. https://biomedpharmajournal.org/vol13no4/gas-chromatography-mass-spectroscopy-gc-ms-analysis-and-phytochemical-screening-for-bioactive-compounds-in-caulerpapeltatagreenalga/ CPME  Caulerpapeltata  GC-Msanalysis Phytochemicals