eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2020-09-25 13 03 1489 1494 10.13005/bpj/2022 34919 article Ghada A Elfadil 1 Elyasa M Elfaki 2 Sulafa O Madani 1 Ezeldine K Abdalhabib 2 Abdelgadir Elmugadam 1 Department of Clinical Chemistry, College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum –Sudan Clinical Laboratory Sciences Department, College of Applied Medical Science, Al-Qurayyat, Jouf University, Saudi Arabia. High-Sensitive C-reactive Protein (hs-CRP) is a well-known inflammatory and cardiovascular disease (CVD) marker. Non-HDL cholesterol concentration in blood are strongly associated with long-term risk of atherosclerotic CVD. Hs-CRP and atherogenic lipids are suggested to be a central feature of cardiovascular disease (CVD), particularly among smokers. Smoking for long duration seems to be correlated with high level of hs-CRP, plasma cholesterol and LDL-C. This study was done to evaluate the plasma levels of hs-CRP, lipid profile, and magnesium in a group of university students with habitual smoking. Eighty current smoker males participated in this cross sectional study. Estimation of plasma hs-CRP was carried out using latex immune turbidimetric method, plasma lipid profile and magnesium by chemical methods using a spectrophotometer (Biosystem 310) and results were computed by using SPSS. Regarding hs-CRP level, 20% (16/80) participants were at high (>3mg/L) risk to CVD; total cholesterol 6.3% (5/80) participants were at  an average greater than 240mg/dL; LDL-C 6.3% (5/80) were at an extremely high risk of greater than 190 mg/dL.  A test group of students who smokes for ten years or more had a significant increase in means of plasma hs-CRP, total cholesterol, LDL-C P value˂ 0.05, while there was a significant decrease in means of plasma HDL-C P value <0.05. Study results revealed that cigarette smoke was associated with considerable changes of hs-CRP, and atherogenic lipids that  were considered as risk factors for cardiovascular disease among young male smokers. https://biomedpharmajournal.org/vol13no3/high-sensitive-c-reactive-protein-and-atherogenic-lipid-levels-in-a-group-of-university-students-with-habitual-smoking/ Smoker   hs-CRP Total cholesterol   LDL-C CVD   magnesium Students