eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2020-03-28 13 1 139 144 10.13005/bpj/1870 30493 article Juala Catherine Jebaraj 1* Bhuvaneswari B 2 Senior Lecturer, Department of Periodontology, Tagore Dental College and Hospital Chennai, India 600 127. Reader, Department of Periodontology, Tagore Dental College and Hospital Chennai, India 600 127. Regenerative medicine aims at replacing lost or defective tissues with new functioning ones. Regenerative medicine uses stem cells which are found in every organ of the body and provides a potential area for research. Pancreatic stem cells have received broad attention as it can be used in the treatment of irreparable disease of the pancreas such as Type I Diabetes Mellitus and pancreatic ductal adenocarcinoma. This review gives a brief insight into the development of pancreatic stem cells, isolation techniques, therapeutic applications and the challenges faced in using adult pancreatic stem cells. https://biomedpharmajournal.org/vol13no1/human-pancreatic-adult-stem-cells-is-it-a-gleam-of-hope-to-patients-with-type-i-diabetes-mellitus/ Adult Pancreatic Stem Cells Pancreatic Ductal Adenocarcinoma Stem Cells Type I Diabetes Mellitus.