eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2018-12-25 11 4 1797 1800 10.13005/bpj/1551 23916 article Alexander Poletaev 1 Federal Research and Clinical Center for Reanimatology and Rehabilitation; MRC Immunculus - Biomarker Group, Moscow, Russia. Blood (blood plasma) is a special all-pervading substance, functionally co-tuning all organs, tissues and cells of the body. To some extent blood is similar to the Ether of the ancients. In addition to performing house-keeping functions, blood is a medium for the transfer of huge amounts of information, which is continuously exchanged between all the compartments and structures of the macro-organism and its microbiome. This information is transmitted mostly in the form of chemical signals (peptides, micro-RNA, extracellular DNA, the products of the microbiome, antibodies, etc.), the totality of which controls lots of biological processes. Blood is not only a controlling, but also a reflecting environment: dynamic changes in the composition of this environment carry information about the smallest changes in the state of individual populations of cells, tissues, organs and the body as a whole. The prospects of practical using of information about the state of the organism, transmitted by blood and reflected in individual’s serum immunoreactivity profiles are analyzed. https://biomedpharmajournal.org/vol11no4/composition-of-the-blood-and-reflection-of-the-health-state-of-human-body/ Autoantibodies Blood Plasma Disease Markers Micro-RNA Peptides Preventive Medicine