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<records>

  <record>
    <language>eng</language>
          <publisher>Oriental Scientific Publishing Company</publisher>
        <journalTitle>Biomedical and Pharmacology Journal</journalTitle>
          <issn>0974-6242</issn>
            <publicationDate>2017-12-21</publicationDate>
    
        <volume>10</volume>
        <issue>4</issue>

 
    <startPage>1735</startPage>
    <endPage>1740</endPage>

	 
      <doi>10.13005/bpj/1286</doi>
        <publisherRecordId>17164</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">The Effect of Noni Leaves Extract (Morinda citrifolia L) on Wound Healing Percentage of Traumatic Ulser in Oral Mucosa of Wistar Rats (Rattus norvegicus) by in Vivo</title>

    <authors>
	 


      <author>
       <name>Sri Rezeki</name>

 
		
	<affiliationId>1</affiliationId>
      </author>
    

	 


      <author>
       <name>Sunnati</name>


		
	<affiliationId>2</affiliationId>

      </author>
    

	 


      <author>
       <name>Nadia Vidirachmilla</name>

		
	<affiliationId>3</affiliationId>
      </author>
    

	


	


	
    </authors>
    
	    <affiliationsList>
	    
		
		<affiliationName affiliationId="1">1Department of Oral Medicine, Faculty of Dentistry, Universitas Syiah Kuala, Banda Aceh- Indonesia. </affiliationName>
    

		
		<affiliationName affiliationId="2">Department of Periodontology, Faculty of Dentistry, Universitas Syiah Kuala, Banda Aceh- Indonesia.</affiliationName>
    
		
		
		
		
	  </affiliationsList>






    <abstract language="eng">Traumatic ulser is a lesion in oral mucosa caused by trauma. Traumatic  ulcer resulting pain can disturb activities and metabolism. Noni leaves (Morinda citrifolia L) contain flavonoid, saponin, and tannin as anti-inflamatory, anti-bacterial, and antioxidant to accelerate healing process.  This research aimed to determine the effect of Morinda citrifolia L leaves extract on healing percentage of traumatic ulcer in oral mucosa. Ulcer was made by put hot burnisher on lower labial mucosa of twelve Rattus norvegicus for a second. They were divided into three groups. First group was given Morinda citrifolia L leaves extract, control group were given triamcinolone acetonide 0,1% and aquades. The research was performed for 10 days by measuring ulcer diameter and applicating extract. Based on Independent-Sampels T Test showed Morinda citrifolia L leaves extract has no significant effect on healing percentage compared to control groups with p = 0.18 and 0.694 (p and gt; 0.05), recovery day for treat group was eighth day and for each control groups were tenth day. Morinda citrifolia L leaves extract has no significant effect on wound healing percentage of traumatic ulcer compare to positive control and negative control.</abstract>

    <fullTextUrl format="html">https://biomedpharmajournal.org/vol10no4/the-effect-of-noni-leaves-extract-morinda-citrifolia-l-on-wound-healing-percentage-of-traumatic-ulser-in-oral-mucosa-of-wistar-rats-rattus-norvegicus-by-in-vivo/</fullTextUrl>

<keywords language="eng">

      
        <keyword>Morinda Citrifolia leaves Extracts</keyword>
      

      
        <keyword>  oral Mucosa Traumatic Ulcer</keyword>
      

      
        <keyword></keyword>
      
</keywords>
  </record>
</records>