eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2017-09-25 10 3 1293 1300 10.13005/bpj/1232 16669 article I. Made Pande Dwipayana 1 I. B. Aditya Nugraha 1 Siswadi Semadi 1 I. Made Suma Wirawan 2 Department of Internal Medicine, Faculty of Medicine, Udayana University-Sanglah General Hospital Denpasar Bali. Faculty of Medicine, Udayana University Denpasar Bali. Male 33 years old patient came with complaint of fever. Positive NS1 and DEN-3 dengue virus were revealed. Patient also with multiple nodules thyroid gland with increased of thyroxine hormone level and Burch Wartofsky 45. Patient was dignosed of thyroid crisis triggered by Den-3 serotype of dengue virus. It was life-threatening case and treated at high care unit. Early diagnosed and prompt treatment safe patient life. https://biomedpharmajournal.org/vol10no3/thyroid-crisis-in-a-toxic-multinodular-goiter-patient-triggered-by-a-den-3-subtype-dengue-infection/ DEN-3 serotype dengue virus multiple nodules thyroid Thyroid crisis thyroxine hormone