eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2017-09-25 10 3 1553 1557 10.13005/bpj/1265 15927 article Shahrzad Nokhbeh Zaeem Islamic Azad University of parand, Parand, Iran. In the present study the effect of selection, and unlimited local communities on changes in gene frequency were investigated.The study found a correlation between the results of the initial gene frequencies based society and generations of selective effect.Size of choice of many the result of recessive gene compared with the effects in different populations during successive generations had little effect. https://biomedpharmajournal.org/vol10no3/effect-of-selection-on-the-genetic-structure-of-the-population-with-the-presence-or-absence-of-genetic-drift/ gene frequency Hardy-Weinberg equilibrium Popsim selection simulation