eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2017-06-20 10 2 837 845 10.13005/bpj/1175 14837 article Sumit Kushwaha 1 Rabindra Kumar Singh 1 Electronics Engineering Department, Kamla Nehru Institute of Technology, Sultanpur, India. Ultrasound (US) Imaging is a boon technology which have a major role in diagnosing the diseases and in image guided surgery. But due to higher frequency absorbed by tissue and skin it cannot penetrate deeply in comparison to lower frequency. So, it gives degraded quality image by echo signals and we get an inferior quality noisy image with some clinical information loss. There are various filters which despeckle the noisy US image and preserve the clinical details. In this paper, we compare the performance of four despeckle filters: Median filter, Lee Filter, Frost Filter, and SRAD filter in terms of PSNR and SSIM performance index under various parameter selection. Finally, we show that SRAD filter is more efficient for removing Speckle noise in comparison to other stated filters, but the performance of median filter is also good enough for speckle noise reduction. https://biomedpharmajournal.org/vol10no2/performance-comparison-of-different-despeckled-filters-for-ultrasound-images/ Ultrasound imaging SRAD filter Meadian filter Lee filter Frost filter