eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2017-06-20 10 2 907 914 10.13005/bpj/1184 14691 article Suha A. AL-Fakhar 1 Clinical Communicable and Infectious Diseases Research Unit /College of Medicine / Baghdad University, Baghdad – Iraq. Circulating immune complexes(CICs) play an important role in many diseases in human. They can cause damage to kidney , joints, skin, and CNS through complement activation with or without local deposition.They can also modulate humoral and cellular immune response through binding to surface receptors of lymphocytes &phagocytes.CICs like activity has been reported in sera from patients with variety of infectious diseases caused by viral, bacterial, protozoal& helminthes. Total 25 patients with different problems of kidney and abortion history (14male&11female) and 25control groups(13 male&12 female).The CICs  was detected by platelets aggregation test (Pl.A.test) and polymorphonuclus (PMN)  were counted automatically. Polymorphonuclear cells  depleted in number in patients with Toxoplasmosis 63.9 percentage and 77.4% percentage in control group ,there is no relationship between  age and % of PMNs (P>0.001) in patients and control group ,13% of patients had CICs detected by PL.A. test and 4% of control group had CICs , There were no of patients had IgM of T.gondii and 8(32%)of them had IgG of T.gondii and 3(12%) of  control group with IgM of T.gondii and 8% of them with IgG of T.gondii. PMN play an important role in the defense against toxoplasmosis and the clearance of CICs from circulation. Most of CICs formed in the circulation contained IgG of T.gondii, since most patients group of the present study did not have IgM of T.gondii but those with  IgG of T.gondii containing IC and the number of PMNs was decreased in large number after T.gondii invasion. https://biomedpharmajournal.org/vol10no2/circulating-immune-complexes-in-relation-to-polymorphonuclear-leucocytes-in-patients-infected-with-toxoplasmosis/ Immune Complexes Leucocytes Polymorphonuclear