eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2017-03-25 10 1 479 480 10.13005/bpj/1133 14175 article Abbas M Abbas 1 Walid G Babikr 2 Aarif Alhassan 3 Nafaa Alnafaa 4 Abdullah I. Aedh 2 Hamdan Alshehri 2 Endocrinologist, Domat Al-gendal Hospital, Aljouf-Saudi Arabia. Assistant Professor of Internal Medicine, Faculty of medicine, Najran University, Saudi Arabia. Cosultant Physician, the diabetes center, Al-jouf, Saudi Arabia. Medical Specialist, Domat Al-gendal Hospital, Aljouf-Saudi Arabia. Neutropenia or [agranulocytosis] means reduced number of circulating neutrophils. It is commonly defined as an absolute neutrophil count [ANC]more than two standard deviations below the normal mean.¹ Neutropenia may be classified as mild (1.0 to 1.5 × 109/L), moderate (0.5 to 1.0 × 109/L), or severe (<0.2 × 109/L), ² the later can markedly increase susceptibility to devastating bacterial infections and a significant increase in mortality risk.³ The association between neutropenia and medical drug use has been recognized since earlier in the twentieth century by American investigators.⁴ Drug-induced hematological disorders can span almost the entire spectrum of hematology, affecting red cells, white cells, platelets, and the coagulation system. https://biomedpharmajournal.org/vol10no1/neutropenia-as-a-probable-side-effect-of-regular-insulin-therapy-a-case-report/ Anticonvulsants  Antihistaminics  Antirheumatics  Neutropenia