{"id":669,"date":"2015-02-15T06:45:54","date_gmt":"2015-02-15T06:45:54","guid":{"rendered":"http:\/\/biomedpharmajournal.org\/?p=669"},"modified":"2020-04-25T07:31:18","modified_gmt":"2020-04-25T07:31:18","slug":"analgesic-and-anti-inflammatory-activities-of-leaf-extract-of-hiptage-benghalensis-l-kurz","status":"publish","type":"post","link":"https:\/\/biomedpharmajournal.org\/staging\/vol2no1\/analgesic-and-anti-inflammatory-activities-of-leaf-extract-of-hiptage-benghalensis-l-kurz\/","title":{"rendered":"Analgesic and Anti-Inflammatory Activities of Leaf Extract of Hiptage Benghalensis (L.) Kurz"},"content":{"rendered":"<p><strong>Introduction<\/strong><\/p>\n<p><em>Hiptage benghalensis <\/em>(L.) Kurz (synonym: <em>Banisteria benghalensis <\/em>and<em> Hiptage madablota <\/em>Gaertn<em>) <\/em>is a herb of the family Malpighiaceae. It is distributed throughout India, Srilanka and the Andaman Islands, Bangladesh and Myanmar to southern China (1). \u00a0The plant is large, evergreen, climbing shrub with brownish bark peeling off in flakes; young parts silky. Leaves opposite, coriaceolate to elliptic-oblong, apex acute to acuminate, base rounded to cuneate and the margins are entire. In central India, flowering occurs mainly between February and April, sometimes also in October; fruiting occurs mainly from April to June. In ayurveda the leaves and bark are considered vulnerary; the leaves are highly regarded for treating skin diseases. The leaf juice possesses insecticidal properties and is used an external application for scabies. The plant is also used in the treatment of chronic rheumatism and asthma (1). This study has been undertaken to evaluate the analgesic and anti inflammatory activity of the methanolic extract of <em>Hiptage benghalensis <\/em>using hot plate and rat paw edema method.<\/p>\n<p><strong>Materials and Methods<\/strong><\/p>\n<p><strong>Plant Material<\/strong><\/p>\n<p>The leaves of <em>H. benghalensis <\/em>were collected from Thirupathi hills, Andhra Pradesh, India. It was authenticated by Prof. V. Raju, Dept of Botany, Kakatiya University, Warangal, India.<\/p>\n<p><strong>Preparation of extrac<em>t<\/em><\/strong><\/p>\n<p>The leaves were cut into small pieces and shed dry and then ground into coarse powder for the maceration process with methanol at room temperature. After exhaustive extraction, the methanolic extract was concentrated under reduced pressure at 50-55 %3<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Introduction Hiptage benghalensis (L.) Kurz (synonym: Banisteria benghalensis and Hiptage  [&#8230;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-669","post","type-post","status-publish","format-standard","hentry","category-vol2no1"],"_links":{"self":[{"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/posts\/669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/comments?post=669"}],"version-history":[{"count":5,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/posts\/669\/revisions"}],"predecessor-version":[{"id":32986,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/posts\/669\/revisions\/32986"}],"wp:attachment":[{"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/media?parent=669"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/categories?post=669"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/tags?post=669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}