{"id":2025,"date":"2015-03-29T07:00:54","date_gmt":"2015-03-29T07:00:54","guid":{"rendered":"http:\/\/biomedpharmajournal.org\/?p=2025"},"modified":"2020-04-26T07:47:04","modified_gmt":"2020-04-26T07:47:04","slug":"proximate-analysis-of-leaves-of-vitex-l-from-shendurjana-ghat-of-warud-tahsil-of-maharashtra-state","status":"publish","type":"post","link":"https:\/\/biomedpharmajournal.org\/staging\/vol4no2\/proximate-analysis-of-leaves-of-vitex-l-from-shendurjana-ghat-of-warud-tahsil-of-maharashtra-state\/","title":{"rendered":"Proximate Analysis of Leaves of Vitex L. from Shendurjana (ghat) of Warud Tahsil of Maharashtra State"},"content":{"rendered":"<p><strong>Introduction<\/strong><\/p>\n<p>India is a rich storehouse of medicinal plants. All natural products can be termed bioactive molecules, as every diverse molecule possesses one kind or multiple kinds of biological oblique pharmacological activities. U.S. and European countries are now realizing the significance of Nature\u2019s Green gift and so they are making patients of herbal drugs.\u00a0 As various parts of <em>Vitex <\/em>L. are used for the treatments of various diseases so has its own identity in traditional drugs practices. Leaves of <em>Vitex<\/em> L. possesses its own identity in medicinal, pharmaceutical and chemical sciences<sup>1-10<\/sup>, due to its anti-hyperglycemic,\u00a0 anti-pyretic, analgesic, anti-microbial, expectorant, stimulates the adrenal cortex, soothes itching and insecticidal properties and\u00a0 Leaves of <em>Vitex<\/em> L. are also used for curing various rheumatic problems\u00a0 and for mosquito repellent.\u00a0 Enormous work on natural products was carried out by research group of D.T.Tayade<sup>11-19 <\/sup>especially on proximate, phytochemical, physiochemical and spectroscopical analysis of various plants and as a part of research work, presently being undertaken in this laboratory on natural products.\u00a0 It appeared sufficient interesting to carry out proximate analysis of the leaves of <em>Vitex<\/em> L. Solubility of the drug directly hamper the drug absorption, transmission and drug effects and moisture and ash contain also affects these properties hence moisture and ash content and cold water, hot water, 1% NaOH, and 1% HCl solubility of <em>Vitex<\/em> L. leaves sample have been investigated.<\/p>\n<p><strong>Preparation of Sample<\/strong><\/p>\n<p>First the site for leaves collection was decided. The whole leaves were collected from same region of Shendurjana (Ghat). Before picking the whole plant, the soil was moistened. The collection of sample was done in between 20<sup>th <\/sup>July2011to 30<sup>th <\/sup>July2011. \u00a0The leaves of\u00a0 <em>Vitex<\/em> L. were separated by scissor and were shed dried. They were dried at room conditions. The leaves were pulverized in grinding mill having a screen of 5mm diameter hole to achieve particle size 40-60 mesh. This fine powder was treated as a sample powder for various analyses. All chemicals used are of A.R. grade.<\/p>\n<p><strong>Moisture content and ash content<\/strong><\/p>\n<p>Silica crucible was taken and it was weighed and kept in oven till it showed constant weight.\u00a0 The leaves sample was analyzed for moisture and ash content by known method<sup>12 <\/sup>and the percentage of the moisture and ash\u00a0 of sample is calculated by applying the following formula,<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-12227\" src=\"https:\/\/biomedpharmajournal.org\/wp-content\/uploads\/2015\/03\/Vol4No2_PROX_Taya_f1.jpg\" alt=\"formula.1\" width=\"488\" height=\"59\" \/><\/p>\n<p><strong>Cold water solubility<\/strong><strong>, hot water solubility, 1% NaOH solubility and 1% HCl solubility <\/strong><\/p>\n<p>The\u00a0 cold water , hot water , 1% NaOH\u00a0 and 1% HCl solubility of leaves sample was analyzed by known method<sup>12<\/sup> and percentage of solubility of each sample is calculated by applying the following formula,<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-12232\" src=\"https:\/\/biomedpharmajournal.org\/wp-content\/uploads\/2015\/03\/Vol4No2_PROX_Taya_f21.jpg\" alt=\"Formula.2\" width=\"421\" height=\"53\" \/><\/p>\n<p>The literature survey on Herbal drugs showed that the results obtained during this study are good.<\/p>\n<p><strong>Table: 1<\/strong><\/p>\n<table style=\"width: 95%;\" border=\"1\" cellspacing=\"0\" cellpadding=\"4\">\n<tbody>\n<tr>\n<td style=\"text-align: center;\" width=\"79\"><strong>Sr\u00a0 No<\/strong><\/td>\n<td style=\"text-align: center;\" width=\"348\"><strong>Parameters<\/strong><\/td>\n<td style=\"text-align: center;\" width=\"162\"><strong>Percentage (%)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" width=\"79\">1<\/td>\n<td style=\"text-align: center;\" width=\"348\">Moisture content<\/td>\n<td style=\"text-align: center;\" width=\"162\">40.2<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" width=\"79\">2<\/td>\n<td style=\"text-align: center;\" width=\"348\">Ash content<\/td>\n<td style=\"text-align: center;\" width=\"162\">2.2<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" width=\"79\">3<\/td>\n<td style=\"text-align: center;\" width=\"348\">Cold water solubility<\/td>\n<td style=\"text-align: center;\" width=\"162\">11.4<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" width=\"79\">4<\/td>\n<td style=\"text-align: center;\" width=\"348\">Hot water solubility<\/td>\n<td style=\"text-align: center;\" width=\"162\">14.5<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" width=\"79\">5<\/td>\n<td style=\"text-align: center;\" width=\"348\">1% NaOH solubility<\/td>\n<td style=\"text-align: center;\" width=\"162\">87.3<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" width=\"79\">6<\/td>\n<td style=\"text-align: center;\" width=\"348\">1% HCl solubility<\/td>\n<td style=\"text-align: center;\" width=\"162\">95.2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>References<\/strong><\/p>\n<ol>\n<li>S. K. Jain Medicinal Plant lore of Tribal of Bastar: Text book of Ethnobotany, 19, (1965), 236-250.<\/li>\n<li>S. K. JainObservation on Ethno botany of the tribal\u2019s of Cent In (Ed) I.C, (1981), 193-198.<\/li>\n<li>S. K. JainMedicinal plants, National books trust Of India Publication, New Delhi (1968).<\/li>\n<li>S. K. Jain J. Advance in plant Science, 13 (1), (2000), 329-339.<\/li>\n<li>A. Pareek J. Phytological Research, 8 (2), (1995), 91-94.<\/li>\n<li>R. Suryanarayan J. of Aryavidyan, 9 (4), (1996), 251-255.<\/li>\n<li>U. S. Patil Ph. D. Thesis Amravati University, Amravati. (2002).<\/li>\n<li>Y. Asakawa Progress in the organic chemistry of Natural product, 65, 1, (1995), 618.<\/li>\n<li>A. Korolkovas Essentials of Medicinal Chemistry, 2<sup>nd<\/sup> Ed., Willey, New York, (1998), 111.<\/li>\n<li>A. Burger Medicinal chemistry, Inter science, New York (1960), 27-37.<\/li>\n<li>D. T. Tayade, J. of Indian Chem Soc., 83, (2006), 1-3 R.S. Shaikh &amp; U. Patil.<\/li>\n<li>R. S. Shaikh Ph. D. Thesis, Amravati University, Amravat. (2006).<\/li>\n<li>D. T. Tayade &amp; Asian J. of Chemistry\u201d, 15, (3 &amp; 4), R. S. Shaikh (2003), 1851-52.<\/li>\n<li>D. T. Tayade &amp; Indian J. applied and pure biology, 18 R. S. Shaikh (2), (2003), 115-157.<\/li>\n<li>D. T. Tayade &amp; U.G.C. sponsored National Conference on, \u201cEmerging R. S. Shaikh Trends in chemical Sciences\u201d, at Shivaji\u00a0 Sci. College Amravati, O-16, (2004), 21.<\/li>\n<li>D. T. Tayade &amp;U.G.C. sponsored National Conference at<\/li>\n<li>S. Shaikh Shivaji college Akola, (2003), 24.<\/li>\n<li>D. T. Tayade, Abstract of National conference<\/li>\n<li>P. Dhakite &amp; sponsored by U.G. C. at Shri. Shivaji<\/li>\n<li>S. Shaikh College Akola, (2003), 23.<\/li>\n<li>P. N. Naskari M. Phil Dissertation, Alagappa University, Karaikudi, (2007)<\/li>\n<li>D.T. Tayade &amp; Abstract of Regional Conference M.B. Bansod \u00a0sponsored by UGC New Delhi at M.F. Mv. Warud (2nd March 2008).<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Introduction India is a rich storehouse of medicinal plants. All  [&#8230;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12],"tags":[],"class_list":["post-2025","post","type-post","status-publish","format-standard","hentry","category-vol4no2"],"_links":{"self":[{"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/posts\/2025","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/comments?post=2025"}],"version-history":[{"count":5,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/posts\/2025\/revisions"}],"predecessor-version":[{"id":33260,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/posts\/2025\/revisions\/33260"}],"wp:attachment":[{"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/media?parent=2025"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/categories?post=2025"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biomedpharmajournal.org\/staging\/wp-json\/wp\/v2\/tags?post=2025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}