Gorlin-Goltz Syndrome (Nevoid Basal Cell Carcinoma Syndrome)-A Case Report

Balachander, L. Malathi, J. Jenita Jacobina and N. Aravindha Babu

Department of Oral Pathology, Sree Balaji Dental College and Hospital, Bharath University, Pallikaranai, Chennai – 600100.

Abstract: Gorlin-Goltz syndrome is a rare autosomal dominant disorder with high penetrance and variable expressivity.It involves multiple organ systems.Pathogenesis of this syndrome is attributed to mutations in the PTCH-1gene. Diagnosis of this syndrome is based on major and minor criteria. The most common finding of this syndrome is multiple odontogenic keratocysts in the jaws. Recurrence of this lesion is most characteristic. A case report of33 years male patient with Gorlin-Goltz syndrome is presented here.

Keywords: Calcification of falx cerebri; Gorlin-Goltz syndrome; Odontogenic Keratocyst

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