MMP- Matrix Metalloproteinase
S. Leena Sankari, R. Jayasri Krupaa, G. M. Kailash Kumar and N. BalachanderDepartment of Oral Pathology, Sree Balaji Dental College and Hospital, Bharath University, Pallikaranai, Chennai - 600100.
Abstract: Matrix metalloproteinase are calcium dependant zinc containing endopeptidase which play important role in the degradation of extra cellular matrix . MMP play major role in cell proliferation , migration , differentiation , apoptosis .Role of MMP in vascular remodeling is also significant. MMP are involved in various diseases such as matastsis of cancer, athroma , arthritis, and tissue ulceration MMP inhibitors have potential therapeutic value in various diseases.
Keywords: metalloproteinase arecalcium; proliferation; migration Back to TOC