Analgesic and Anti-Inflammatory Activities of Leaf Extract of Hiptage Benghalensis (L.) Kurz
Baburao Bhukya¹*, Rama Narsimha Reddy Anreddy² and Krishna Mohan Gottumukkala¹¹Department of Pharmacognosy and Ethnopharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal - 506 009 India.
²Department of Pharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal - 506 009 India.
Corresponding Author E-mail: babupharma79@gmail.com
Abstract: In present work, the methanolic extract of leaves of Hiptage benghalensis (MEHB) was screened for the analgesic (using hot plate test and acetic acid-induced writhing test in mice) and anti-inflammatory (using rat paw edema test) activity at the doses of 200 and 400 mg/kg body weight. A significant (p<0.0005) analgesic effect was observed with 200 mg/kg and 400 mg/kg in both tests. The maximum anti-inflammatory response was produced at 3 hr and 2 hr with MEHB doses of 200 and 400 mg/kg of respectively. These results suggest that the methanolic extract of Hiptage benghalensis has exhibited significant analgesic and anti-inflammatory effects, which were comparable with standard drugs.
Keywords: Hiptage benghalensis; analgesic; anti-inflammatory; writings; Carrageenan Back to TOC