Anti-Inflammatory Effects of Hydro-Methanolic Extract of Ficus Carica
Huma Ali1*, Jitender Monga1, Lokendra Gupta2, Aniruddh Singh1, Sailesh Narayan3 and Zeeshan A. Siddiqui4¹Department of Research Jawaharlal Nehru Cancer Hospital and Research Center, Idgah Hills, Bhopal - 462 001 India.
2 Government Gandhi Medical College, Hamidia Road, Bhopal India.
3 Sagar Institute of Pharmacy and Technology, Near Air Port, Bhopal - 462 021 India.
4 Department of Mathematics and Computer Science BSSS,
Corresponding Author E-mail: zeehuma_ali@yahoo.com
Abstract: In this article, we report for the efficiency of Ficus carica extract in the treatment against inflammation. The methanolic extract of Ficus carica leaves were investigated for the evaluation of their anti-inflammatory potential on fomalin-induced paw oedema in Wister rats. Leaf extract of Ficus carica in dose 200mg/kg (P < 0.05) and 500mg/kg (P < 0.001) on orally administration gave significant reduction of rat paw oedema at all assessment times. The Ficus carica leaf extract showed maximum inhibition of 66.43% at the dose of 500mg/kg after 4 hrs. Where as the standard drug showed 70.78% of inhibition. These observations evealed that Ficus carica has significant anti-inflammatory property.
Keywords: Antiinflammatory effects; Ficus carica; hydro-methanolic extract Back to TOC