Advancement of Nanofibers in Wound Healing: A Review
Venkatesan Kotteeswaran*
, Mrinalini Saravanakumar, Roshelle Mary Alexander , Radhika S Nairand Kavin M RamnathDepartment of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, India.
Corresponding Author E-Mail: venkatek@srmist.edu.in
Abstract: The field of wound healing is currently experiencing a ground-breaking transformation with the introduction of nanofiber technology. This groundbreaking discovery has the potential to revolutionize regenerative medicine and tissue engineering worldwide, effectively meeting the growing need for innovative and affordable healthcare solutions. This comprehensive review explores the evolution and utilization of nanofibers to enhance wound healing. Nanofibers, known for their ability to mimic the extracellular matrix of human tissue, play a crucial role in facilitating cell growth and wound repair. The review explores sophisticated techniques like electrospinning and the integration of bioactive agents such as antibiotics and growth factors with nanofibers. It emphasizes on the precision with which these nanofibers are customized to address specific therapeutic requirements. Additionally, the review sheds light on the use of both natural and synthetic polymers in crafting biocompatible nanofibers, which significantly reduces healing time while ensuring optimal aesthetic recovery, meeting the expectations of patients with minimal scarring. It emphasizes the synergy of expertise from materials science, biology,and clinical practices in propelling nanofiber-based therapies from the laboratory to the forefront of clinical care. Through this succinct overview, we aim to underscore the immense potential of nanofibers in transforming wound care. We are offering a glimpse into a future where effective and efficient healing is within reach, marking a remarkable leap forward in the global quest for advanced healthcare solutions.
Keywords: Anti-Microbial; Nanofibers; Skin repair; Tissue engineering; Wound dressing; Wound healing Back to TOC