Effect of Artemisia Vulgaris on Liver of Albino Mice Exposed to Cisplatin
Alaa Saadi Abbood*
, Anwer Jaber Faisaland Mokhtar jawad Al-ImamIraqi center for cancer and medical genetic research / Mustansiriyah university. Baghdad, Iraq.
Corresponding Author E-mail: Alaasabbood@uomustansiriyah.edu.iq
Abstract: The herb Arte(also known as Artemisia V.) is widely used to treat a variety of illnesses, including gastrointestinal disorders, infections, and fungal infections. The antibacterial component that makes this ingredient so beneficial and essential for treating septicemia is the prebiotic. This study looked at how Artemisia vulgaris L. protected rats' livers from the toxic treatment cisplatin. In virtual medicine, cisplatin is frequently employed. Numerous forms of human cancer, such as advanced cancer, uterine cancer, esophageal cancer, advanced privacy, and ovarian cancer, have been successfully treated with it. infection from other illnesses, like disease. In this experiment, thirty 25–30 g white secretive mice aged 12 weeks were used. 72 hours were spent soaking blood tissue samples in 4% paraformaldehyde before they were paraffin embedded. Hematoxylin-eosin (H, E) staining was applied after the sections were cut into 3-m pieces and embedded in paraffin wax. Establishing with the extraction of Artemisia vulgaris L 400 mg/kg/day of extract is the greatest efficiency technique, as the separated groups revealed. This proved the extract's efficiency. This finding offers thorough and widely reported support for the use of purifications like A. vulgaris in the medical treatment of systemic poisoning with additional benefits like definite therapeutic effects and potent histochemical in the treatment of cancerous tissues.
Keywords: Artemisia vulgaris, Cisplatin; H and E stain; Hepatoprotective; Hepatotoxicity Back to TOC