Non-Invasive Bio-impedance Diagnostics: Delving into Signal Frequency and Electrode Placement Effects
G Hari Krishnan1*, Sheeba Santhosh2, G Mohandass3 and T Sudhakar4

1Department of Electrical and Electronics Engineering, Sree Vidyanikethan Engineering College, Mohan Babu University, Tirupati, Andhra Pradesh, India.

2Department of Electronics and Communication Engineering, Panimalar Engineering College, Chennai, India

3Department of Biomedical Engineering, Saveetha School of Engineering, Chennai, India.

4Department of Biomedical Engineering, Sathyabama Institute of Science and Technology, Chennai, India.

Corresponding Author E-mail: haris_eee@yahoo.com

Abstract: Electrical characterization of biological tissues offers a promising non-invasive approach to understanding tissue properties. This research rigorously examines how bio-impedance values are influenced by the frequency of the input signal and the strategic placement of electrodes. Utilizing the capabilities of the AD5933 evaluation board by Analog Devices, the study spanned a frequency range from 1KHz to 200 KHz. The results highlighted a significant decrease in impedance with increasing frequency, a trend attributed to the capacitive characteristics of cell membranes. Moreover, the specific distance between electrodes was identified as a crucial factor affecting measurement accuracy. Given these findings, the adaptation of this technique in healthcare settings, particularly in diagnostics, could offer enhanced precision, underscoring its potential relevance in clinical practice.

Keywords: Bio-Impedance; Electrode Positioning; Electrical Properties; Input Signal Frequency; Pathological Conditions; Tetra Polar Electrode

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