In-vitro Anti-bacterial and Anti-cancer activity of Ocimum Tenuiflorum L. leaf Extract Induced Silver Nanoparticles – A study of Characterization Cum Evaluation
R. Karthikeyan 1*
, G. Haema 1, V. Vijayan 1, V. Alamelu1, M. Sakthiganapathy 1, S.Shanmuganathan1, Binoy Varghes Cheriyan 2 , R. Saravanan3 and P. Vijayarajkumar41School of Pharmacy, Sri Balaji Vidyapeeth, SBV Campus, Pillayarkuppam, Puducherry, India
2 Faculty of Pharmacy, Bharath Institute of Higher Education and Research, India
3Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai, India.
4Faculty of Pharmaceutical Sciences , UCSI University,UCSI Heights, 56000 Kuala Lumpur, Malaysia
Corresponding Author E-mail: professorrkn @gmail.com
Abstract: Silver nanoparticles were combined with Ocimum Tenuiflorum L. green and purple (Krishna Tulasi) assortments using a single advance that was eco-friendly. Ultraviolet-Visible spectrophotometer, Fourier transform Infra-red, X-Ray Diffraction, Scanning Electron Microscope (SEM), and Energy Dispersive X-ray spectroscope was used to describe the particle nature of integrated AgNps (EDX). A variety of modifications confirmed the nanoparticle arrangement and UV-Visible spectroscopy was used to quantify the Surface Plasmon retention band. In the FTIR, the presence of the aromatic ring's C-H vibration is comparable to the presence of flavonoids and carbonyl gathering in the C-O stretch vibration. The inserted silver nanoparticles can clearly be seen under an SEM microscope, and the particles are estimated to be between l and 100 nm in size. The Energy Dispersive X-ray spectra demonstrate the nanomaterial’s quality. Union is traditional and viewed as proficient as far as response time as well as practicality. The combined nanoparticles were exposed to Anti-microbial and Anti proliferative investigations by in-vitro strategies and showed a portion of the subordinate movement against specific microbes and cancer cells.
Keywords: Anti-bacterial; Anti-cancer study; Characterization; Ocimum tenuiflorum; Particle size; Silver nanoparticles; Zeta potential Back to TOC