The Association between Vitamin D Status and Diabetic Complications in Type 2 Diabetic Patients
Tahani Hassan1*
, Nadine Alhumaidan1, Basher Yousef1, Mariam Alsalhi1, Abdulrahman Albulayhi2 and Sultan Al Harbi3 1Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraidah, KSA.
2Diabetes and Endocrinology Center ,Buraydah, King Fahad Specialist Hospital (KSA).
3Diabetes and Endocrinology Center, Unaizah, King Saud Hospital (KSA).
Corresponding Author E-mail:tahani-ibrahim@hotmail.com
Abstract: Diabetes can affect many different organs in the body and may lead to serious complications. Many studies related vitamin D deficiency to the occurrence Type 2 diabetes complications. However, the link between diabetic complications and vitamin D deficiency is under debate. Therefore this study aimed to evaluate the clinical relevance of vitamin D levels on diabetic complications. This retrospective cross-sectional study was conducted on 252 patients followed at King Fahd Specialist Hospital in Buraydah and King Saud Hospital in Unaizah, Saudi Arabia. The participants were divided into five groups: Non-diabetic group, diabetic without complications, diabetic nephropathy, diabetic peripheral neuropathy, and diabetic retinopathy. 78.3% of diabetic neuropathy showed vitamin D deficiency compared to diabetic nephropathy (75%), retinopathy (56.9%), and diabetics without complications (31.4%). Vitamin D deficiency was higher in diabetic patients with complications (69.8%) compared to those without complications (31.4%). Moreover 39.2% of diabetics without complications showed normal vitamin D level compared with 13.4% of diabetics with complications. The results showed that vitamin D deficiency was significantly associated with diabetic complications.
Keywords: Diabetic complications; Type 2 diabetes; Vitamin D deficiency Back to TOC