A Flavonoid out of Tephrosia Purpurea Extract and its Antimicrobial Effect
Vandana Singh*1, R. C. Saxena2 and A. K. Singh¹1Pest Control and Ayurvedic Drug Research Laboratory, Vidisha (India).
2Department of Chemistry, R.G.P.V. University, Bhopal (India).
Corresponding Author E-mail: vandanatomar@yahoo.com
Abstract: Flavonoids are present widely in Angiospermic plants and are associated with several pharmacological activities including antibacterial, antidiabetic, antifungal, anti-allergic and anti-oxidant activities. Flavonoids because of their low toxicity compared to other active plant compounds can be ingested in significant quantities by human beings in their diet. Flavonoid can initially prevent the ageing, cancer and inflammation effectively rather than cure because they inhibit the occurrence of oxidative stress in the cell. Tolerance to ultraviolet and altered behavior of T, B, NH and mast cells and neutraphills in their presence assure the activation of immune system. Body’s action against them as foreign compound induces phase II enzyme which are mutagens and carcinogens eliminating. The present article shows the significance of flavonoids as potential drug, emphasizing their extraction out of Indian ethnomedicinal plant Tephrosia purpurea because of its easy availability and study of MIC value of particular flavonoid found effective on very much prevailed microbe born diseases.
Keywords: Immunomodulatory; ethnomedicinal; minimum inhibitory concentration; Antimicrobial Back to TOC