Hybrid Model: Deep Learning Method for Early Detection of Alzheimer’s Disease from MRI Images

Anuradha Vashishtha^1*, Anuja Kumar Acharya² and Sujata Swain³

School of computer engineering, KIIT University, Bhubaneshwar, India.

Corresponding Author E-mail: er.anuradhavashishtha30@gmail.com

Abstract: Alzheimer's disease is a neurodegenerative brain disease that kills neurons. The global prevalence of the disease is gradually growing. In all leading countries, it is one of the senior citizens' leading causes of death. So, much research shows that early detection of illness is the most critical factor in improving patient care and treatment outcomes. Currently, AD is diagnosed by the manual study of magnetic resonance imaging, biomarker tests, and cognitive tests. Machine learning algorithms are used for automatic diagnosis. However, they have certain limits in terms of accuracy. Another issue is that models trained on class-unbalanced datasets often have poor results. Therefore, the main objective of the proposed work is to include a pre-processing method before the hybrid model to improve classification accuracy. This research presents a hybrid model based on a deep learning approach to detect Alzheimer’s disease. Which, we are using the SMOTE method to equally distribute the classes to prevent the issue of class imbalance. The hybrid model uses Inception V3 and Resnet50 to detect characteristics of Alzheimer's disease from magnetic resonance imaging. Finally, a dense layer of convolution neural network is used for classification. The hybrid approach achieves 99% accuracy in classifying MRI datasets, which is better than the old work. These results are better than existing approaches based on accuracy, specificity, sensitivity, and other characteristics.

Keywords: Alzheimer's disease (AD); Convolution neural network (CNN); InceptionV2, ResNet50; Magnetic resonance imaging (MRI).

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