Analysis of Metals in Cataract Fluid of Jordanian Patients by Using the Inductively Coupled Plasma Optical Emission Spectrometry
Fawaz Al-Saraireh1, Abdul-Wahab R. Hamad2*, Mousa Khames Mezel Magarbeh2, Tayel A. AL-Hujran2, and Mutasem Elfalah11College of Medicine, Mutah University, Al-Karak, Jordan.
2College of Pharmacy, Mutah University, Al-Karak, Jordan.
Corresponding Author E-mail: wahabhamad2004@yahoo.com
Abstract: Background: The study was completed to determine the level of the following metals (Sodium (Na), Potassium (K), Phosphorus (P), Calcium (Ca), Manganese (Mn), Iron (Fe), Cobalt (Co), Copper (Cu), Zinc (Zn), Selenium (Se), and Cadmium (Cd)) in different cataractous human lenses. Materials and Methods: Five Samples had collected from the normal individuals healthy people and 25 suffered from cataracts at the Italian Hospital, Al-Karak, Jordan. This study had conducted between November 2020 and October 2021 on 30 individual subjects. Samples fluid from the Cataract sufferers had been gathered, the data was analyzed using Microsoft excels and SPSS software program new version. The trace elements concentration withinside the aspirated fluid were measured with the inductively coupled plasma optical emission spectrometry – Mass (ICP-MS), best controlled with certified standards. Results: The mean values of copper were (12.9±12.4) and (7.4±9.7) for patients and control groups respectively. The average mean values of Cd were found to be (5.9 ±2.4) and (4.6 ± 2.4). The cadium, copper, manganese, magnesium and potassium levels were significantly higher in the catarctous groups. The others elements were lower in the catarctous group than control. Conclusion: Results showed significant change in some metallic elements concentration with cataract. These consequences can be beneficial for understanding and identifying the reasons that can play a function withinside the initiation and improvement of cataract. These factors deficiency may also have some suggestions to diets and diseases via its appropriate concentrations and its consequences on various organs parameters. It appears that the estimation of serum or plasma concentration of these metals may also assist in research and remedy of other diseases in both genders.
Keywords: Cataract; ICP-Mass; Lens; Metals; Trace Elements Back to TOC