Ethanol Extract of Brassica Rapa Attenuate the Complete Freund’s Adjuvant-Induced Inflammation in Rats
Bhupesh Chandra Semwal*
, Neha Singh and Shilpi PathakDepartment of Pharmacology, Institute of Pharmaceutical Research GLA University, Mathura, U.P. -281406 India
Corresponding Author E-mail: bhupesh115@gmail.com
Abstract: Turnip is an ancient edible plant belongs to family Braaicacaceae. Traditionally it is used for the treatment of various disorders such as diabetes, hepatotoxicity, ulcer, and anti-inflammatory activity. Therefore the current investigation was attempted to investigate the anti-inflammatory activity of Brassica rapa root extract against complete fluids adjuvant induced inflammation in experimental animals. The Ethanol extract of Brassica rapa was prepared by a hot extraction procedure and phytochemical analysis of different extract was done by different chemical tests. Daily oral treatment of indomethacin, and extract for twenty-one days after three days of CFA administration significantly decrease the paw volume, hepatic biomarkers as well as ameliorated the level of a hematological parameter such as hemoglobin, RBC, WBC, ESR and bodyweight of experimental animals. From the result of the current investigation, it can be concluded that the Brassica rapa extract possesses anti-inflammatory activity. Further study is required to explore the mechanism responsible for its anti-inflammatory activity.
Keywords: Arthritis; Brassica rapa; CFA; ESR; Hemoglobin Back to TOC