Study of Serum Electrolytes in Type 2 Diabetes Mellitus Individuals in Rural Tertiary Care Hospital in Kancheepuram District.
V. Santhosh1, D M. Gomathi1, A. Khadeja Bi1, S. Suganya1, G. Gurulakshmi2 and Manjula Devi N3

1Department of Biochemistry, Karpaga Vinayaga Institute of Medical Science and Research Center.

2Government Medical college,Virudhunagar.

3Department of Biostatistician, Karpaga Vinayaga Institute of Medical Science and Research Center.

Corresponding Author E-mail: gomathisurendran01@gmail.com

Abstract: Aim: To measure the levels of  Serum electrolytes (Na+, K+ ,Cl )in type II DM individuals and to compare it with healthy controls. Methods: A case control study was conducted at Medicine Department, from March 2019 to September 2019. A total of 60 patients ,comprised of  30 confirmed type II DM patients as cases and  30  healthy individuals of similar criteria were treated as controls. In both the groups,biochemical measurement of Serum electrolytes (Na+, K+ ,Cl ),FBS was studied and the results were compared. Results: Inindividuals with Diabetes mellitus sodium and chloride showed insignificant alterations.There was an increase in serum potassium levels which was found  to be statistically highly significant (p-value less than or equal to 0.05) . The drift of  potassium from  intracellular space to extracellular space leads to Hyperkalaemia which is due torenal impairment, insulin deficiency or hypertonicity. Conclusion: This study concludes that there is significant association of  potassium  with hyperglycemic crisis in patients with  type 2 diabetes mellitus. Thus serum electrolytes has to be routinely monitored in diabetic individuals since electrolyte derangements are markedly found in uncontrolled diabetes.

Keywords: Diabetes Mellitus; Hyperkalaemia; Hyperglycemic

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