Screening of Stem Extracts of Plumbago Zeylanica for Phytochemical, Antimicrobial and Anti-Arthritis Activity

Amin Mir^1*, Anuj Kumar², Reeta Chauhan³ and Mohammad Waqar Ashraf⁴

¹Department of Mathematics and Natural Sciences, Prince Mohammad Bin Fahd University, Al Khobar, Saudi  Arabia

²Department of Mathematics Govt. Degree College Kotdwar Pauri Garhwal.

³Department of Mathematics Raj Kumar Goel Institute of Technology, Ghaziabad.

⁴Department of Mathematics and  Natural Sciences, Prince Mohammad Bin Fahd University, AlKhobar, Saudi Arabia.

Corresponding Author E-mail: mohdaminmir@gmail.com

Abstract: The plant Plumbago Zeylanica is known for its traditional medicinal use because of its wide phytochemical constituency. On same basis its screening for anti-microbial and anti-arthritis activity was carried out. The results showed that the stem of Plumbago Zeylanica could be used as best remedy against bacterial and fungal originated diseases. Among plant extracts, chloroform extract showed highest rate of inhibition against all the concerned bacterial strains followed by petroleum ether extract. The water extract did not show much response as an antimicrobial agent. Also the antifungal activity was observed for all the extracts, but ethanolic extract showed more inhibition potential followed by petroleum ether extract. The results of anti-arthritis activity shows, lowest IC₅₀ (46.55) value for water extract, hence high inhibition potential, followed by ethanolic extract (IC₅₀) 48.50. Over all the plant showed good response as biomedicine against microbial originated diseases and against arthritis.

Keywords: Anti-Arthritis; Anti-Microbial;  IC₅₀ ; Plumbago Zeylanica; Phytochemistry.

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