Systematic and Symptomatic Review for Parkinson’s Disease
Vinayak Majhi1*
, Sudip Paul1and Goutam Saha21Department of Biomedical Engineering, North-Eastern Hill University, Shillong, India, 793022
2Department of Information Technology, North-Eastern Hill University, Shillong, India, 793022
Corresponding Author E-mail : majhi.vinayak@gmail.com
Abstract: After two hundred years of the Shaking Palsy by Dr. James Parkinson, we have revealed many factors and causes behind Parkinson’s disease (PD). Before Shaking Palsy the symptoms were known as some disorders. 5000 years ago in Ayurveda, the Indian medical manuscript and 2500 years ago in Nei Ping, the first Chinese medical manuscript some disorders were mentioned those are similar to PD and also several treatment procedures were also described. This proves that PD is not a disease that evolved only in modern industrial age. But it is true that, after Shaking Palsy, this PD comes into spotlight of the modern medical practices. To understand this disease we need to go through the complete etiology of PD including Genetical and Environmental factor that may lead us to the different causative factors of PD. Each factor has its unique signification and outburst as a multiple combination of different Parkinsonian symptoms. In this review we will discuss about all possible etiological factors related to PD with different Parkinsonian symptoms categorized with motor and non-motor symptoms. Before going to the brief review, we will also discuss about several milestone researches which actually open a new window in PD research on its time.
Keywords: Etiology of Parkinson’s disease; Mitochondria; Motor Symptoms; Non-Motor Symptoms; Substantia Nigra Back to TOC