Estimation of Fasting Serum Levels of Glucose, Zinc, Copper, Zinc /Copper Ratio and Their Relation to the Measured Lipid Profile in Autistic Patients and Non-Autistic Controls in Jordan
Abdulrahman Al-Bazzaz, Kahtan A-Dahir, Abdulsalam Almashhadani and Israa Al-Ani*Faculty of Pharmacy, Al-Ahliyya Amman University, Jordan
Corresponding Author E-mail : ialani@ammanu.edu.jo
Abstract: "Autism spectrum disorder" refers to a range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication. This study aimed to measure the fasting serum levels of glucose, zinc , copper, zinc / copper ratio and their correlations to the measured lipid profile in matched Non-Autistic by age, gender and body mass index with Autistic patients in Jordan. To find a correlations between the studied parameters that might help in understanding the biochemical changes that may lead to autism also to open away for medical management and treatment of autism. Fasting blood samples were taken from both matched groups (35 each with age 4-12 years) then analyzed the above parameters and data was treated statistically by SPPS while Correlations were determined by Pearson’s test. The study revealed that there was significant changes in levels and correlations especially in zinc and zinc/copper ratio in relation to triglycerides and high density lipoprotein in autistic patients.
Keywords: Autism; Lipid profile; Zinc and Copper Back to TOC