A Study on Analysis of Cardio Vascular Risk Factors in Chronic Alcoholics
Shanmugapriya V1
and Karthikeyan D21Department of Biochemistry Vinayaka Mission’s Medical College, Karaikal, Puducherry UT – 609609, India
2Department of Microbiology Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamilnadu – 636308, India
Corresponding Author E-mail: priyasri_1011@yahoo.com
Abstract: Alcoholism is now an emerging social and national health problem among adolescents and middle aged population. Alcohol consumption has doubled in the recent years and has increasing its complications. To analyze the metabolic variations in chronic alcoholics which include their BMI, liver function test, lipid profile, inflammatory markers, antioxidants level, insulin level and atherogenic index. The chronic alcoholics had increased BMI with grade 1 obesity with mean value of 30.8±2.4. The mean total cholesterol level (mg/dl) in cases was 232 ± 22.4. The mean HDL level (mg/dl) showed a significant variation among the study group as 38.8±7.8. The mean LDL and NHDL in cases were 148.6 ±15 and 170±17.8 respectively. The mean serum insulin level in study population was 22.36±5.8. The GGT level was increased as expected with mean value 112±13.9. Lipid peroxidation marker MDA was markedly increased in alcoholics with mean value of 14.6± 1.7. All the biochemical parameters in chronic alcoholics were significantly altered when compared to normal non-alcoholic individuals. Alcoholic patients were found to be dyslipidemic, grade I obese, oxidative stress with low levels of anti-oxidants, insulin resistant and prone to cardiac risks by developing atherogenesis.
Keywords: Alcoholism; antioxidants; cardiac risks; inflammatory markers Back to TOC