The Effect of Manna of Hedysarum Prescription on the Decrease of Bilirubin Level in Lcteric Neonates
Mohammad Reza SharifDepartment of Pediatrics, Kashan University of Medical Sciences, Kashan. I.R
Corresponding Authors E-mail: dr.sharifmd@yahoo.com,
Abstract: Hyperbilirubinema is one of the common problems that causes the most case of hospitalization of neonates. Manna of hedysarum is a plantar medicine that has been prescribed as medication in the traditional medicine. This medication has not been examined systematically through a well-controlled clinical research. The purpose of this research was to examine the effect of Manna of hedysarum on the level of bilirubin of neonates and eliminating the need to hospitalization. In this double blind clinical research, the neonates that were visited by a pediatrician and did not need hospitalization were randomly assigned into two groups of receiving extract of Manna of hedysarum or placebo prepared by Barij Essence Co. Statistical analysis was performed by using SPSS:PC version 12:.0. The result of analysis using ANOVA repeated measure indicated that there was no significant difference in the level of bilirubin after 24 hours of treatment between the groups. However, there was significant difference in bilirubin level of the treatment group by Manna of hedysarum compared to the placebo group after 48 and 72 hours following the treatment ( p=0.005 and p=0.0001). The bilirubin level of the group treated by Manna of hedysarum was less than the placebo group. The results of this research indicated that using Manna of hedysarum decreases the level of bilirubin in outpatient neonates that suffer from hyperbilirubinemia. Further research is necessary before firm suggestion to use this medication for inpatient or outpatient neonates that are afflicted to hyperbilirubinemia.
Keywords: Manna of hedysarum; Hyperbilirubinemia; Neonates; Outpatients Back to TOC