Simple Virilization Type of Classic Congenital Adrenalhyperplasia: Case Report

I Made Pande Dwipayana^1,2, Karismayusa Sudjana³, Siswadi Semadi¹, Ketut Suastika¹, Made Ratna Saraswati¹ and Wira Gotera¹

¹Division of Endocrinology and Metabolism, DepartmentofInternal Medicine, Facultyof Medicine, Udayana University-Sanglah General Hospital Denpasar Bali.

²Doctoral Programme in Medical Science, Facultyof Medicine, Udayana University Denpasar Bali.

³Internal Medicine Programme, Facultyof Medicine, Udayana University-Sanglah General Hospital Denpasar Bali.

Corresponding Author E-mail: pande_dwipayana@unud.ac.id

Abstract: We have reported a case of 21 year old patient with congenital adrenal hyperplasia that manifestated with ambiguous genitalia and other signs of androgen excess. Chromosome analysis revealed 46 XX. Laboratory examination and imaging showed high level of 17-hydroxyprogesterone, undeveloped uterus, two ovaries with follicles, no testicles, no prostate, and mass at upper side of both kidney with irregular border confirmed the diagnosis. It was planned to give glucocorticoid therapy to the patient to suppress androgen level, genital reconstruction surgery and psychosexual therapy to reared as a woman, but she refused all suggestions because she wanted to be considered a man.

Keywords: Androgen excess, Congenital Adrenal Hyperplasia, Genital reconstruction, Glucocorticoid therapy

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