Apelin and some Biomarkers in Females with Metabolic Syndrome

Shaimaa S. Mutlak¹, Vean Sabah Ali¹ and Radhwan M. Hussein²

¹Department of Basic Science, College of Dentistry, University of Baghdad, Iraq.

²College of Pharmacy /University of Ahl AL-Bayt. Iraq.

Corresponding Author E-mail: shaimaaphdbio@gmail.com

Abstract: The metabolic syndrome (MS) is one of the main public fitness issues around the world. The superiority of MS was increasing in parallel with weight problems and diabetes worldwide. Many of the various standards for the identification of MS, its most important additives are atherogenic dyslipidemia, insulin resistance, high blood pressure and abdominal weight problems. A new bioactive adipokine (Apelin), which play a very important role (vital role) in controlling glucose homeostasis, dyslipdemia, cardiovascular diseases and obesity. The aim of this study is to study the relativity between apelin and metabolic syndrome in women. The research start by chosen 75 females were involved in this study (15 control and 60 had metabolic syndrome) divided into four groups and were classified according to the criteria of International Diabetes Federation 2005. All subjects were reported and it was contain anthropometric and biochemical investigation. Blood samples collected from all subjects at Baghdad teaching hospital during September 2015 to April 2016. Serum apelin was estimated using ELISA technique. While TG, HDL, HbA1C and FBG serums were measured using colorimetric methods. It was concluded that high significant elevated in apelin concentration in women with MS make suggested that apelin has potential role in metabolic syndrome.

Keywords: Apelin; BMI;; HDL; HbA1C Metabolic Syndrome;  Triglyceride WC;

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