Influence of Boron Compounds on Chromium-Induced Hemorheology Disorders in Rats
Marat Iztleuov, Azhar Zhexenova, Saule Abdildayeva, Gulmira Iztleuova, Aliya Zhiengalieva, Akmaral Altayeva, Gulaym Taskozhina, Jamila Jumagalieva, Zhanat Umirzakova
, Mahabbat Shurenova and Akmoldir SisembayevaWest Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan.
Corresponding Author E-mail: zhanat_us@mail.ru
Abstract: The authors of this study evaluated the protective influence of boric acid on chromium-induced blood rheology disorders. The experiment was carried out on Wistar rats, which were divided into three groups: Group 1 - the control group; Group 2 - rats with simulated chromium-induced hemorheology disorders; Group 3 - rats, in which boric acid was administered throughout 10 days on the background of chromium-induced hemorheology disorders. In rats with simulated chromium-induced hemorheology disorders, one could observe decrease in deformability of red blood cells and in hematocrit level on the background of increased aggregation, peroxide hemolysis and osmotic fragility of red blood cells. In the third group, corrective application of boric acid inhibited development of blood rheology disorders, i.e., its protective action was revealed.
Keywords: Boric Acid; Hemorheology; Potassium Dichromate; Protective Action Rat; Back to TOC