Changes in Systemic Blood Pressure and Serum Xanthine Oxidase Activity Induced by The Stimulation of Alcohol Metabolism by Fructose in Man
U. E. Uzuegbu¹, C. Amadi² and A. U. Onochie³¹Department of Medical Biochemistry, Delta State University, Abraka Nigeria.
²Department of Medicine, Lagos University Teaching Hospital, Lagos Nigeria.
³Department of Biochemistry, Anambra State University, Uli Nigeria.
Abstract: The stimulation of ethanol oxidation and hence, its clearance from bloodstream by the administration of fructose significantly (P<0.05) increased both systemic blood pressure and serum xanthine oxidase activity when compared with the basal (0 hour) value, 15 hours after ingestion. The use of fructose to fasten the removal of alcohol from blood may be highly associated with the risk of hypertension (high blood pressure) elicited by the increased activity of serum xanthine oxidase. Further investigations and the role of dietary supplements and interventions are required to enhance the understanding of the metabolic effects of fructose in stimulating alcohol elimination from the body.
Keywords: Ethanol; Xanthine oxidase; Blood pressure; Fructose Back to TOC