The Correlation of Uric Acid Levels with Glycemic Control in Type II Diabetic Patients
Walid G Babikr1, Amar B Elhussein2, Ahmad Abdelraheem1, A Magzoub3,Hatem Mohamed4 and Mohammed Alasmary1
1Department of medicine- College of Medicine – Najran University.
2Department of Biochemistry – Nile College– Khartoum Sudan.
3Department of physiology- College of Medicine – Najran University.
Abstract: The association between serum uric acid levels and glycemic control in diabetic patients was not fully clarified. This study aimed at investigating the association between levels of serum uric acid and glycemic control in type II diabetic patients.The study included 270 diabetic patients and 136 healthy controls, recruited from the outpatient clinic of Najran University Hospital and Najran area respectively. Uric acid, creatinine, BUN and FBS were measured by COBAS INTEGRA 400 andRoche diagnostics commercial kits. HbA1c was estimated using Nycocard HbA1c Method. Weight and height were measured using standardized scale for weight and height and then BMI was calculated.In diabetic patients, serum uric acid level was found to correlate positively with HbA1c(r=0.135, p=0.026). We found a statistically insignificant difference in mean creatinine concentration between the two study groups. There was a slight gender variation in mean serum uric acid level which was more evident in diabetics than healthy controls. In conclusion, serum uric acid level has an adverse effect on glycemic control in type II diabetic patients. High serum uric acid levels have been reported to be a risk factor for chronic kidney disease, hypertension and metabolic syndrome. Nevertheless, the association with glycemic control in diabetic patients was not fully studied. To investigate the association between levels of serum uric acid and glycemic control in type II diabetic patients. The study included 270 diabetic patients and 136 healthy controls, recruited from the outpatient clinic of Najran University Hospital and Najran area respectively. Uric acid, creatinine, BUN and FBS were measured by COBAS INTEGRA 400 andRoche diagnostics commercial kits. HbA1c was estimated using Nycocard HbA1c method. Weight and height were measured using standardized scale for weight and height and then BMI was calculated.
Keywords: Uric acid; Creatinine; BUN; FBS; HbA1c; BMI Back to TOC