Comparative Anti-Oxidant Activity Studies of Buchanania Lanzan Methanolic Extract
Shalini Kapoor Mehta*, Swarupananda Mukherjee and B. JaiprakashKrupanidhi College of Pharmacy, Chikkabelandur, Karmaleram, Bangalore - 35 India.
Corresponding Author E-mail:shalini1710@yahoo.com
Abstract: Traditionally used medicinal plants used for antioxidant activity has significance as it can target ROS (Reactive Oxygen Species) implicated in many disease conditions. Drugs of plant origin are gaining increasing popularity sense it is directly related to increasing resistance of an organism to non specific stress. Some plants like Buchanania lanzan are found to be potential herbs. In vitro screening of methanolic extracts of the leaf and bark of Buchanania lanzan was carried out using DPPH, ABTS and H2O2 radicals. The in vitro screening was carried out by using discoloration assay, which is evaluated by addition of anti oxidant to a solution of colored free radical. Antioxidant activity of both the extracts determined against DPPH, ABTS and H2O2 radicals. The bark and leaf extracts exhibited potent inhibition against ABTS radical generation. The extracts showed good activity against DPPH radical, but in H2O2 method leaf extract failed to show inhibition even at highest test concentration, whereas bark extract, inhibited H2O2 moderately.
Keywords: Buchanania lanzan; DPPH; ABTS; ROS; free radical Back to TOC