Carbapenems, Linezolid, Teicoplanin Utilization Evaluation in a Large Teaching Based Hospital (Shahid Rajaie Heart Center, Tehran): A Quality Improvement Study
Bahram Fariborz Farsad1, Naser Hadavand1*, Hanieh Salehi2 and Farzaneh Shekari21Pharm.D, BCPS, Assistant Professor, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical sciences, Tehran, Iran.
2Department of Pharmacology , Pharmaceutical Sciences Branch , Islamic Azad University , Tehran , Iran.
Corresponding Author E-mail: Hadavandn@yahoo.com
Abstract: The Aim of this study is to access the number of inappropriate usages of post CABG antibiotics such as, Carbapenems, Teicoplanin and Linezolid in Shahid Rajaie Hospital and to apply antibiotic practice guidelines and strategies to reduce inadequate treatment while determining their impact on patient outcomes. This retrospective study was performed at special wards of Shahid Rajaie Hospital. The program was conducted since March to August 2015. All of the patients which were on Imipenem, Meropenem, Linezolide or Teicoplanin as an empiric treatment or based on culture results were considered in the study. The results of this study indicated that among 136 in-patients who had taken at least one of these antibiotics including Imipenem, Meropenem, Linezolide or Teicoplanin, antimicrobial prescription assumed inappropriate for 63 patients (46.32%), The most common reason was incorrect dosage (16.39%)and the least one was not being drug of choice(2.4%).this inappropriateness was occurred mostly in diagnosis of respiratory infection , skin infection and sepsis. The results of this study demonstrates the need for revision in program of prescribing antibiotics in the direction of using antibiotic practice guidelines especially regarding usage of Teicoplanin and Meropenem in specific complication such as respiratory infection and skin infection.
Keywords: Carbapenems; Linezolid; Teicoplanin; Utilization; Evaluation Back to TOC