The Impact of Green Tea (Camellia Sinensis) on the Amount of Gonadotropin Hormones (LH, FSH) in Immature Female Rats Poisoned with Cadmium Chloride
Babamaleki Mahmood*, Mokhtari Mokhtar, Sharifi EsfandiarDepartment of Biology, Islamic Azad University, Kazerun Branch, Kazerun, Iran. Corresponding Author : Email: mahmoodbabamalekii67@gmail.com
Abstract: Cadmium chloride as an environmental and industrial contaminant element duo to the its cumulative nature in body organs, as well as production of reactive oxygen species is considered toxic for many tissues and sexual organs and can disrupt hormonal harmony of these organs. Thus, it is tried in many studies to reduce possible side effects of cadmium chloride using medicinal plants. Green tea is a medicinal plant which is due to its antioxidant properties can be examined in many studies. The aim of the current study is also to investigate the edible effect of green tea (Camellia sinensis) on the gonadotropin hormones (LH, FSH), in immature female rats poisoned with cadmium chloride. the used animals were 48 immature female Wistar rats, which were divided into 6 groups of 8 each, including a control group that received no treatment; a blank that received physiological serum or green tea solvent; an experimental group 1 that received 400 mg/lit cadmium chloride; an experimental group 2 that orally received 14 mg/lit green tea by for 21 days; an experimental group 3 that first received 400 mg/lit cadmium chloride for 21 days, then received orally 7 mg/lit green tea for 21 days; an experimental group 4 that first received 400 mg/lit cadmium chloride for 21 days and then orally received 14 mg/lit green tea for 21 days. Then, the rats of different groups were bled to measure FSH and LH hormones. The obtained data were then tested by One-Way Analysis of Variance (ANOVA) were determined at a significant level (P< 0.05) by SPSS software version 15. the mean results of FSH and LH hormones in the experimental 1 shows significant reduction compared to the control and blank. While the experimental 2 shows significant increase compared to the control and blank, and these amounts in the experimental 3 and 4 show significant increases compared to the experimental 1. the results of the study show some beneficial effects of green tea against toxicity of cadmium chloride on gonadotropin hormones and its use is recommended to reduce toxicity of cadmium chloride.
Keywords: Green Tea, LH; FSH; Cadmium Chloride; Female Rats Back to TOC