Association of the Red Cell Distribution Width with Complete Blood Count, Glycated Hemoglobin and Vitamin D in Patients with Type 2 Diabetes Mellitus- Across Sectional Study
Asaad Ma. Babker 1*
, Rania Saad Suliman2 , Nour A. M. Farajallah1, Fahad Al-Qahtani3 , Dhafer Mubarak Alhadeb3, Qubaa Ahmed Elzubair4, Kiran S Gopinath1 and Anass M. Abbas51Department of Medical Laboratory Sciences, College of Health Sciences, Gulf Medical University, Ajman, UAE
2Department of Clinical Laboratory Sciences, Prince Sultan Military College for Health Sciences, Dhahran, Saudi Arabia
3Department, King Fahad Military Medical Complex, Dhahran, Saudi Arabia
4Alemadi Hospital, Doha, Qatar
5Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Saudi Arabia
Corresponding Author E-mail: azad.88@hotmail.com
Abstract: The current study was aimed to assess the association of the Red Cell Distribution Width (RDW) with Glycated haemoglobin (HbA1C) and Vitamin D in Patients with Type 2 Diabetes Mellitus to provide insight into the potential physiological mechanisms and predictive significance of RDW fluctuations in patients with heart failure who are diabetic. Material &Methods: The cross-sectional design of this study was utilized to investigate a cohort of 150 patients who had received a diagnosis of type 2 diabetes mellitus. The assessment centered on the evaluation of comorbidities, red cell distribution width (RDW), and glycemic management in addition to vitamin D levels. Information was gathered via questionnaires, encompassing demographic details as well as medical history. Blood samples were assessed for RDW, total blood count, HbA1c, and Vitamin D concentrations using automated analyzers. The statistical analysis was performed utilizing version 27 of SPSS. Results: The study found low relationships between HbA1c and Vitamin D (r = -0.033, p = 0.691), RDW and HbA1c (r = -0.046, p = 0.573), and RDW and Vitamin D (r = -0.128, p = 0.118). Furthermore, Vitamin D had diverse connections with CBC values, suggesting a complex link within the setting of type 2 diabetes mellitus. Conclusion: The findings of the current study indicated an association between the RDW and RBCs, Hb and Red blood cell indices (HCT, MCV, MCH and MCHC) in patients with T2DM. The RDW could therefore serve as potential marker for the management of patients with T2DM.
Keywords: Glycated Hemoglobin; Vitamin D; Red Cell Distribution Width Back to TOC